发布日期：2024-02-06

制定者：Peter Mandl, Maria Antonietta D’Agostino, Victoria Navarro-Compán, Irina Geßl, Garifallia Sakellariou, Abhishek Abhishek, Fabio Becce, Nicola Dalbeth, Hang-Korng Ea, Emilio Filippucci , Hilde Berner Hammer , Annamaria Iagnocco , Annette de Thurah, Esperanza Naredo , Sebastien Ottaviani , Tristan Pascart, Fernando Pérez-Ruiz,  Irene A Pitsillidou, Fabian Proft , Juergen Rech,  Wolfgang A Schmidt ,  Luca Maria Sconfienza,  Lene Terslev,  Brigitte Wildner,  Pascal Zufferey,  Georgios Filippou

出处：欧洲风湿病防治联合会

Ann Rheum Dis. 2024 May 15;83(6):752-759. doi: 10.1136/ard-2023-224771.

摘要：

Objective: To formulate evidence-based recommendations and overarching principles on the use of imaging in the clinical management of crystal-induced arthropathies (CiAs)

Methods: An international task force of 25 rheumatologists, radiologists, methodologists, healthcare professionals and patient research partners from 11 countries was formed according to the EULAR standard operating procedures. Fourteen key questions on the role of imaging in the most common forms of CiA were generated. The CiA assessed included gout, calcium pyrophosphate deposition disease and basic calcium phosphate deposition disease. Imaging modalities included conventional radiography, ultrasound, CT and MRI. Experts applied research evidence obtained from four systematic literature reviews using MEDLINE, EMBASE and CENTRAL. Task force members provided level of agreement (LoA) anonymously by using a Numerical Rating Scale from 0 to 10

Results: Five overarching principles and 10 recommendations were developed encompassing the role of imaging in various aspects of patient management: making a diagnosis of CiA, monitoring inflammation and damage, predicting outcome, response to treatment, guided interventions and patient education. Overall, the LoA for the recommendations was high (8.46–9.92)

Conclusion: These are the first recommendations that encompass the major forms of CiA and guide the use of common imaging modalities in this disease group in clinical practice

目的：制定关于在晶体诱导的关节病（CiAs）的临床管理中使用影像学的循证建议和总体原则

方法：根据欧洲抗风湿病联盟（EULAR）的标准操作程序，成立了一个由来自11个国家的25位风湿病学家、放射科医生、方法学家、医疗保健专业人员和患者研究合作伙伴组成的国际工作组。他们提出了关于最常见的晶体诱导性关节病（CiA）影像学角色的14个关键问题。评估的CiA包括痛风、焦磷酸钙沉积病和碱性磷酸钙沉积病。影像学检查方式包括常规X线摄影、超声、CT和MRI。专家们利用MEDLINE、EMBASE和CENTRAL数据库从四篇系统性文献综述中获取的研究证据进行了应用。工作组成员使用0到10的数字评定量表匿名提供了他们的一致性程度（LoA）。

结果：制定了五项总体原则和十项建议，涵盖了影像学在患者管理的各个方面的作用：确诊CiA、监测炎症和损伤、预测结果、治疗反应、引导干预和患者教育。总体而言，这些建议的一致性程度（LoA）很高（8.46–9.92）。

结论：这些是首个涵盖CiA主要形式的建议，并指导临床实践中该疾病组常见影像学方式的使用。